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Development of a highly selective EP2-receptor agonist. Part 1: Identification of 16-hydroxy-17,17-trimethylene PGE₂ derivativesTANI, Kousuke; NAGANAWA, Atsushi; TODA, Masaaki et al.Bioorganic & medicinal chemistry. 2002, Vol 10, Num 4, pp 1093-1106, issn 0968-0896Article

Design and synthesis of a highly selective EP4-receptor agonist. Part 2 : 5-Thia and 9β-halopg derivatives with improved stabilityMARUYAMA, Toru; ASADA, Masaki; KONDO, Kigen et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 15, pp 2033-2035, issn 0960-894XArticle

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 1: Discovery and exploration of the carboxyamide side chainASADA, Masaki; OBITSU, Tetsuo; NAKAI, Hisao et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 1, pp 80-90, issn 0968-0896, 11 p.Article

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A practical synthesis and biological evaluation of 9-halogenated PGF analoguesTANI, Kousuke; NAGANAWA, Atsushi; OGAWA, Mikio et al.Bioorganic & medicinal chemistry. 2002, Vol 10, Num 6, pp 1883-1894, issn 0968-0896Article

Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonistsASADA, Masaki; OBITSU, Tetsuo; NARITA, Masami et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 8, pp 2639-2643, issn 0960-894X, 5 p.Article

Discovery of new chemical leads for selective EP1 receptor antagonistsNAGANAWA, Atsushi; SAITO, Tetsuji; OHUCHIDA, Shuichi et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 16, pp 5562-5577, issn 0968-0896, 16 p.Article

Development of a highly selective EP2-receptor agonist. Part 2: Identification of 16-hydroxy-17,17-trimethylene 9β-chloro PGF derivativesTANI, Kousuke; NAGANAWA, Atsushi; KONDO, Kigen et al.Bioorganic & medicinal chemistry. 2002, Vol 10, Num 4, pp 1107-1114, issn 0968-0896Article

Design and synthesis of a highly selective EP4-receptor agonist. Part 1 : 3,7-dithiaPG derivatives with high selectivityMARUYAMA, Toru; ASADA, Masaki; TODA, Masaaki et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 15, pp 2029-2031, issn 0960-894XArticle

An Improved Synthesis of the Selective EP4 Receptor Agonist ONO-4819OHTA, Chisa; KUWABE, Shin-Itsu; SHIRAISHI, Tai et al.Journal of organic chemistry. 2009, Vol 74, Num 21, pp 8298-8308, issn 0022-3263, 11 p.Article

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonistsNAGANAWA, Atsushi; MATSUI, Toshiaki; NAKAI, Hisao et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 19, pp 6628-6639, issn 0968-0896, 12 p.Article

Discovery of a new class of potent, selective, and orally active prostaglandin D₂ receptor antagonistsTORISU, Kazuhiko; KOBAYASHI, Kaoru; OHUCHIDA, Shuichi et al.Bioorganic & medicinal chemistry. 2004, Vol 12, Num 20, pp 5361-5378, issn 0968-0896, 18 p.Article

Discovery of new chemical leads for prostaglandin D₂ receptor antagonistsTORISU, Kazuhiko; KOBAYASHI, Kaoru; IWAHASHI, Maki et al.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 17, pp 4557-4562, issn 0960-894X, 6 p.Article

Combined effects of prostaglandin E receptor subtype EP₁ and subtype EP₄ antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout miceKITAMURA, Tomohiro; ITOH, Masaki; NODA, Tetsuo et al.Cancer science. 2003, Vol 94, Num 7, pp 618-621, issn 1347-9032, 4 p.Article

Design and synthesis of a selective EP4-receptor agonist. Part 1: Discovery of 3,7-DithiaPGE₁ derivatives and identification of their ω chainsMARUYAMA, Toru; ASADA, Masaki; SHIRAISHI, Tai et al.Bioorganic & medicinal chemistry. 2002, Vol 10, Num 4, pp 975-988, issn 0968-0896Article